NEWS

Cortex Announces $1.5 Million Private Placement

Cortex Receives Delisting Notification from NYSE Amex

Cortex Reports Third Quarter Operating Results

Cortex’s CEO to Present at Rodman & Renshaw’s Eleventh Annual Healthcare Conference on September 10, 2009

Cortex Reports Second Quarter Operating Results

Cortex Pharmaceuticals Announces Financing

Cortex Annual Shareholder Meeting Notification

Cortex Receives Notice of Non-Compliance From NYSE Amex For Continued Listing Requirements

Cortex Reports First Quarter Operating Results

Cortex Announces Closing of Financing

Cortex Announces Financing

Cortex Reports Fourth Quarter and Year End Operating Results

Cortex Pharmaceuticals Announces Corporate Restructuring and Workforce Reduction

Studies in Animals Demonstrate AMPAKINE Molecules Reverse Memory Loss in Huntington’s Disease

Cortex’s CEO to Present at the Roth Capital Partners 21st Annual Orange County Growth Stock Conference

Cortex Receives UK Regulatory Approval to Initiate a Clinical Study in Sleep Apnea with its AMPAKINE CX1739

Cortex Reports Third Quarter Operating Results

Cortex’s CEO to Present at Rodman & Renshaw’s Tenth Annual Healthcare Conference on November 10, 2008

Cortex’s AMPAKINE® Research in Opioid–Induced Respiratory Depression makes Windhover’s Top 10 List of Neuroscience Projects Available for Partnering

Cortex’s AMPAKINE Compound, CX717, Achieves Primary Endpoints in Second Phase IIa Respiratory Depression Study in Germany

Cortex Reports Second Quarter Operating Results

Cortex’s AMPAKINE Molecule CX717 Has Positive Effects in Opiate–Induced Respiratory Depression in a Phase IIa Clinical Study

Cortex to Provide Top Line Data for CX717 Clinical Trial for the Prevention of Opiate-Induced Respiratory Depression in Humans

CORTEX and Top Alberta Government officials meet to Discuss progress on AMPAKINE Compounds AT The 2008 Bio Conference

Alberta pharmaceutical industry expands international partnerships

Cortex Pharmaceuticals Announces Management Changes

Cortex Annual Shareholder Meeting Notification

Cortex Reports First Quarter Operating Results

Cortex Initiates Enrollment in Opiate Induced Respiratory Depression Clinical Trial in Germany Today

Cortex Reports Fourth Quarter and Year End Operating Results

Cortex Receives Approval from German Regulatory Authority to Proceed With two Clinical Trials for AMPAKINE® CX717 for the Acute Treatment of Respiratory Depression due to Opiate Analgesics

Cortex’s CEO to Present at the Roth Capital Partners 20th Annual Orange County Conference

Cortex’s CEO Roger Stoll to Speak at the Bank of Montreal’s Focus on Healthcare Conference

Cortex Reports Third Quarter Operating Results

Cortex’s CEO to Present at Rodman & Renshaw’s Ninth Annual Healthcare Conference On November 5, 2007

Cortex to Provide Shareholder Update and Host Conference Call on October 31, 2007

Cortex Names Pierre V. Trân, MD, MMM, Chief Medical Officer and Vice President of Clinical Development

FDA’s Psychiatric Division has Rejected Cortex’s Request to Study CX717 in Phase IIb ADHD Study

Cortex to Provide Shareholder Update and Host Conference Call on September 19, 2007

Cortex Files Ampakine CX717 IND for ADHD

Cortex’s CEO Roger Stoll to Speak at the Bear Stearns 20th Annual Healthcare Conference, New York, on September 10th, 2007

Cortex’s CEO Roger Stoll to Speak at the Roth Capital Partners New York Conference on September 5, 2007

Cortex Completes $14.2 Million Registered Direct Offering

Cortex to Raise $14.2 Million in Registered Direct Offering

Cortex Reports Second Quarter Operating Results

Cortex to Resume Clinical Trial with AMPAKINE® CX717 in Alzheimer-PET Scan Study After FDA Approves Protocol with Higher Doses of Drug

Cortex and the University of California, Irvine Extend Exclusive Licensing Agreement

Cortex's CEO to Present at the JMP Securities Research Conference and Cortex's COO to Present at the Neurotech Industry Investing & Partnering Conference

Cortex and The University of Alberta complete patent license agreement

Cortex Reports First Quarter Operating Results

Cortex Annual Shareholder Meeting Notification

Cortex’s AMPAKINE CX717 Toxicology Data Package Submitted To FDA

Cortex Reports Fourth Quarter and Year End Operating Results

Cortex has licensed its AMPAKINE technology to Organon BioSciences N.V. Schering-Plough Corporation will acquire Organon BioSciences.

Cortex Pharmaceuticals Appoints Les Street, Ph.D., Head of Medicinal Chemistry and Steven A. Johnson, Ph.D., VP of Pre-Clinical Development Becomes an Officer of Cortex

Update On Cortex’s CEO Presentation At The Roth Capital Partners 19th Annual Conference

Cortex’s CEO To Present At The Roth Capital Partners 19th Annual Orange County Conference

Cortex Completes $5.6 Million Direct Equity Placement

Cortex To Raise $5.6 Million in Direct Equity Placement